Neuroprotective Strategies after Neonatal Hypoxic Ischemic Encephalopathy
نویسندگان
چکیده
منابع مشابه
Neuroprotective Strategies after Neonatal Hypoxic Ischemic Encephalopathy
Neonatal hypoxic ischemic encephalopathy (HIE) is a devastating disease that primarily causes neuronal and white matter injury and is among the leading cause of death among infants. Currently there are no well-established treatments; thus, it is important to understand the pathophysiology of the disease and elucidate complications that are creating a gap between basic science and clinical trans...
متن کاملHypothermia: a neuroprotective therapy for neonatal hypoxic-ischemic encephalopathy.
t he incidence of hypoxic ischemic encephalopathy in the United States is 2.8/1000 live births of which 10–15% of the infants succumb and 25–30% suffer permanent neurologic damage: mental retardation, cerebral palsy and epilepsy. The incidence is tenfold higher in the developing world [1-3]. Experimental evidence has confirmed that HIE is an evolving process lasting hours to weeks. Understandin...
متن کاملHypoxic-Ischemic Neonatal Encephalopathy: Animal Experiments for Neuroprotective Therapies
Hypoxic-ischemic neonatal encephalopathy and ensuing brain damage is still an important problem in modern perinatal medicine. In this paper, we would like to share some of the results of our recent studies on neuroprotective therapies in animal experiments, as well as some literature reviews. From the basic animal studies, we have now obtained some possible candidates for therapeutic measures a...
متن کاملCerebellar vermian atrophy after neonatal hypoxic-ischemic encephalopathy.
BACKGROUND AND PURPOSE Although pathologic evidence of cerebellar injury due to birth asphyxia is well described, neuroimaging evidence is sparse. The primary purpose of this retrospective study was to evaluate the early and late imaging findings in the cerebellum of patients who had neonatal hypoxic-ischemic encephalopathy with thalamic edema shown by neonatal CT. The secondary aims were to va...
متن کاملStem Cell Therapy in Hypoxic Ischemic Encephalopathy
Introduction there are one million deaths from asphyxia in newborn annually. Management of this newborn is only supportive. Autologuse stem cell therapy may reduce mortality and long term morbidity. Outcome of asphyxiated newborn is related to damage CNS cells. Stem cells prevent Apoptosis and induce repairmen of injured neurons. Methods in a review study all article related to three keyword...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2015
ISSN: 1422-0067
DOI: 10.3390/ijms160922368